Table 2. The effects of DCBEI on the levels of neurotransmitters in hippocampus of APP/PS1 mice.

	WT	APP/PS1	APP/PS1
			DCBEI (mg/kg)
			160	320
Ach (×10-2) (pmoL/mgprot)	1.7±0.2	1.3±0.2#	2.2±0.4*	2.1±0.5*
AChE (×10-2) (nmoL/mgprot)	6.1±0.9	8.2±0.9#	7.6±0.5	7.8±1.2
ChAT (×10-2) (pmoL/mgprot)	2.3±0.2	2.4±0.4	2.6±0.5	5.9±0.6**
Gln (μmol/mgprot)	0.5±0.2	0.8±0.2#	0.6±0.1	0.7±0.2
GABA (×10-3, μmol/mgprot)	3.1±0.5	2.4±0.4#	4.1±0.7**	4.5±0.8***
iso-Hyd (μg/mgprot)	657.7±118.2	492.8±87.8##	871.1±139.0***	988.8±198.5***
5-HT (ng/mgprot)	114.0±10.6	90.1±16.1##	151.9±22.2***	181.4±57.9**
NA (ng/mgprot)	3.6±0.5	2.4±0.3###	3.8±0.5**	4.5±0.7***
HIS (ng/mgprot)	7.1±0.4	5.4±0.8##	9.7±1.4***	10.9±1.2***
5-HIAA (ng/mgprot)	9.9±2	7.6±1.1#	15.0±2.1***	18.2±5.3**

All date is expressed as mean ± S.D. (n=10). ^#P < 0.05, ^##P < 0.01 and ^###P < 0.001 compared with WT group; ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001 compared with APP/PS1 group.