Table 3. The effects of DCBEI on the levels of oxidative stress related factors in serum and hippocampus of APP/PS1 mice.
| WT | APP/PS1 | APP/PS1 | |||
| DCBEI (mg/kg) | |||||
| 160 | 320 | ||||
| SOD (pg/mL) | 50.3±1.98 | 41.3±1.1 | 42.0±3.3 | 42.8±2.9 | |
| Serum | MDA (pmoL/mL) | 1.9±0.15 | 2.6±0.3# | 1.9±0.2* | 2.0±0.2* |
| CAT (pg/mL) | 28.7±1.3 | 25.2±1.2 | 26.7±1.9 | 31.4±2.7* | |
| GSH-Px (pg/mL) | 89.9±6.6 | 83.3±5.8 | 88.5±10.6 | 82.6±8.8 | |
| ROS (U/mL) | 387.2±19.7 | 438.0±13.4# | 384.8±12.7* | 394.5±25.7* | |
| Hippocampus | SOD (pg/mgprot) | 18.3±2.6 | 13.6±1.2# | 17.1±1.6* | 17.9±1.6* |
| MDA (×10-2, pmoL/mgprot) | 36.8±2.7 | 44.4±2.7 | 44.3±7.3 | 44.2±3.1 | |
| CAT (pg/mgprot) | 9.5±1.39 | 7.6±0.733# | 8.5±0.9* | 9.4±1.2* | |
| GSH-Px (pg/mgprot) | 34.9±3.0 | 34.2±2.8 | 42.4±3.4* | 39.0±3.9* | |
| ROS (U/mgprot) | 133.6±9.4 | 136.7±8.3 | 106.9±12.8* | 106.2±11.2* | |
All date is expressed as mean ± S.D. (n=10). #P < 0.05 compared with WT group; *P < 0.05 compared with APP/PS1 group.