Skip to main content
. 2021 Apr 4;13(8):11257–11280. doi: 10.18632/aging.202811

Table 2. Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis for the differential genes.

Description Generatio Pvalue p.adjust qvalue geneID
Fat digestion and absorption 6/57 4.80E-07 8.45E-05 7.84E-05 ABCG5/DGAT2/MOGAT3/APOA1/FABP1/ABCG8
Cholesterol metabolism 5/57 2.48E-05 0.002180513 0.002021408 APOA2/ABCG5/LPA/APOA1/ABCG8
PPAR signaling pathway 5/57 0.000199794 0.011721233 0.010865975 APOA2/SCD5/ACSL6/APOA1/FABP1
Protein digestion and absorption 5/57 0.000531847 0.023401248 0.02169374 COL12A1/COL3A1/SLC7A9/COL1A2/COL1A1
AGE-RAGE signaling pathway in diabetic complications 5/57 0.000672758 0.023681078 0.021953152 NOX4/AKT3/COL3A1/COL1A2/COL1A1
Central carbon metabolism in cancer 4/57 0.001465681 0.042993318 0.039856246 AKT3/KIT/PFKP/SLC2A2
Platelet activation 5/57 0.001768727 0.044470846 0.041225963 AKT3/PRKG1/COL3A1/COL1A2/COL1A1
ECM-receptor interaction 4/57 0.003392436 0.074633591 0.069187838 TNC/COL1A2/COL1A1/THBS2

*KEGG, Kyoto Encyclopedia of Genes and Genomes; PPAR, peroxisome proliferators-activated receptor; ECM, extracellular matrix. GeneRatio: Annotation of genes in this pathway, annotation of genes in all KEGG pathways, and the ratio of the two; BgRatio: All genes annotated to pathway, all genes annotated to KEGG pathways, and the ratio of the two. Pvalue: P value of hypergeometric test; P.adjust: The P value corrected by multiple hypothesis testing; Qvalue: Q value; GeneID: geneID annotated to the pathway; Count: The number of genes annotated to the pathway.