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. 2021 Apr 20;13(8):11752–11761. doi: 10.18632/aging.202869

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Copyright: © 2021 Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Zileuton suppresses neuronal apoptosis after SAH. (A, C, D) Effect of Zileuton with and without LY294002 on expression levels of pro-apoptotic Bax and anti-apoptotic Bcl-2 (n = 6 per group). ^*P < 0.05 vs sham group and ^&P < 0.05 vs SAH group, ^#P < 0.05 vs SAH + Zileuton group. (B, E) TUNEL analysis of the effect of Zileuton with and without LY294002 on the incidence of apoptosis among neurons after SAH. Original magnification, 400×, n = 6 per group. ^*P < 0.05 vs sham group and ^&P < 0.05 vs SAH group, ^#P < 0.05 vs SAH + Zileuton group.