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. 2021 Apr 16;13(8):10955–10972. doi: 10.18632/aging.202970

Table 2. Summarized effect of HBOT on cardiometabolic impairment in pre-diabetic rats after induction of aging by D-gal.

Cardiometabolic impairments Sham HBOT
NDV HFV NDDg HFDg HFV NDDg HFDg
Metabolic disturbance graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg
Aging Marker graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg
Autonomic imbalance graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg
LV dysfunction graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg
Mitochondrial impairment graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg
Inflammation graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg
Apoptosis graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg
Oxidative stress graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg
Autophagy graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i002.jpg graphic file with name aging-13-202970-i003.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg graphic file with name aging-13-202970-i001.jpg

NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal; HBOT, hyperbaric oxygen therapy.

One up arrow indicates impairment of cardiometabolic parameters, two up arrows indicate severe impairment of cardiometabolic parameter and double headed arrow indicates no significant change in cardiometabolic parameters compared to NDV rats.