Table 2.
GCF Biomarker Levels of Subjectsa
| GCF Biomarker |
Overall, Mean (SD) |
Normal Weight, Mean (SD) |
Obese, Mean (SD) |
P Value |
| GCF flow rate, μL/min | 0.92 (0.20) | 0.86 (0.17) | 0.89 (0.21) | .06b |
| Adiponectin, ng/mL | 6481.07 (4439.60) | 6683.80 (3224.31) | 6278.34 (5480.16) | .258c |
| Leptin, pg/mL | 353.03 (166.17) | 298.30 (81.69) | 407.77 (209.19) | .009c |
| Resistin, ng/mL | 518.35 (278.51) | 484.14 (280.57) | 552.56 (279.73) | .435c |
| MPO, ng/mL | 453.52 (302.87) | 459.47 (319.76) | 447.57 (293.67) | .773c |
| CRP, ng/mL | 141.06 (286.95) | 33.02 (121.61) | 249.10 (360.31) | .075c |
| MMP8, ng/mL | 3539.26 (943.77) | 3310.32 (775.50) | 3768.19 (1057.75) | .223c |
| MMP9, ng/mL | 4452.52 (1434.44) | 4117.81 (1209.17) | 4787.23 (1590.90) | .020c |
| TIMP1, ng/mL | 99.82 (67.62) | 103.98 (76.43) | 95.66 (59.34) | 1.000c |
| MMP8/TIMP1 | 21.35 (12.70) | 20.86 (14.00) | 21.84 (10.86) | .603c |
| MMP9/TIMP1 | 15.54 (9.28) | 15.10 (10.46) | 15.99 (7.61) | .435c |
| RANKL, pg/mL | 1192.24 (681.41) | 1040.51 (324.95) | 1343.97 (894.56) | .624c |
a
Significant results are indicated in bold. SD indicates standard deviation; GCF, gingival crevicular fluid; MPO, myeloperoxidase; CRP, C-reactive protein; MMP8, matrix metalloproteinase-8; MMP9, matrix metalloproteinase-9; TIMP1, tissue inhibitor of metalloproteinase 1; RANKL, receptor activator of nuclear factor kappa-B ligand.
b
Independent t-test.
c
Mann-Whitney U-test.