TABLE 2.

Univariable Association of Clinical and Stress CMR Indices With Outcome Using a Fine and Gray Competing Risk Model

	Primary Outcome		Secondary Outcome
	HR (95% CI)	p Value	HR (95% CI)	p Value
Demographics
Age, per yr	1.01 (1.00–1.03)	0.06	1.01 (1.00–1.02)	0.10
Female	0.58 (0.42–0.81)	0.002	0.79 (0.64–0.97)	0.02
BMI, per kg/m2	1.00 (0.98–1.02)	0.89	1.00 (0.99–1.02)	0.76
Cardiac risk factors
Hypertension	1.53 (0.98–2.39)	0.06	2.05 (1.50–2.79)	<0.0001
Hypercholesterolemia	1.02 (0.72–1.45)	0.90	1.23 (0.97–1.54)	0.09
Diabetes mellitus	1.67 (1.21–2.31)	0.002	1.51 (1.23–1.87)	<0.001
Smoking	1.82 (1.32–2.51)	<0.001	1.56 (1.27–1.93)	<0.0001
Family history of CAD	0.75 (0.52–1.08)	0.12	1.00 (0.80–1.25)	0.98
Number of cardiac risk factors	1.36 (1.19–1.56)	<0.0001	1.40 (1.29–1.53)	<0.0001
CAD Consortium score, basic	1.02 (1.01–1.03)	<0.0001	1.01 (1.01–1.02)	<0.0001
History of PCI	2.73 (1.98–3.76)	<0.0001	2.48 (2.02–3.06)	<0.0001
History of MI	4.26 (3.08–5.88)	<0.0001	2.79 (2.23–3.48)	<0.0001
History of CHF	3.71 (2.60–5.30)	<0.0001	2.72 (2.12–3.48)	<0.0001
Stress CMR
LVEF, per % Δ	0.97 (0.96–0.98)	<0.0001	0.97 (0.96–0.98)	<0.0001
LVEDVI, per ml/m2 Δ	1.01 (1.01–1.02)	<0.0001	1.01 (1.01–1.02)	<0.0001
LVESVI, per ml/m2 Δ	1.02 (1.01–1.02)	<0.0001	1.01 (1.01–1.02)	<0.0001
Ischemia+	3.41 (2.46–4.73)	<0.0001	3.30 (2.67–4.08)	<0.0001
Extent of ischemia, per segment	1.10 (1.07–1.14)	<0.0001	1.11 (1.08–1.14)	<0.0001
LGE+	4.10 (2.97–5.65)	<0.0001	3.24 (2.64–3.97)	<0.0001
Extent of LGE, per segment	1.11 (1.08–1.14)	<0.0001	1.09 (1.07–1.11)	<0.0001
Abnormal CMR, ischemia or MI	3.85 (2.77–5.36)	<0.0001	3.59 (2.91–4.42)	<0.0001

Primary outcome was defined as cardiovascular death or nonfatal MI. Secondary outcome was defined by a composite of cardiovascular death, nonfatal MI, hospitalization for unstable angina or CHF, and late unplanned coronary arterial bypass surgery.

^{+ =}present;

^{Δ =}difference;

CHF = congestive heart failure; CI = confidence interval; HR = hazard ratio; other abbreviations as in Table 1.