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. Author manuscript; available in PMC: 2021 May 10.
Published in final edited form as: Am J Transplant. 2020 Jul 1;20(12):3285–3293. doi: 10.1111/ajt.16095

Figure 2: On-going and future applications of CRISPR technology for solid organ transplantation.

Figure 2:

A) Applications of CRISPR-based technologies at cellular level for tolerance induction. B) CRISPR mediated research strategies. C) Xenotransplantation from CRISPRed transgenic animals and CRISPRed chimeric animal for solid organ. D) Potential ex-vivo CRISPR application for solid organs inside the pump. (ECD: Expanded Criteria Donor, SCNT: Somatic Cell Nuclear Transfer, HSC: hematopoietic stem cell, MSC: Mesenchymal Stem Cell).