Extended Data Table 3. Vaccinated donors tested at V1 and V2 in ELISpot and whole blood assays.

Donors tested at V1 and/or V2 for T cell responses to spike using the ELISpot assay and/or the whole blood assay. Where an assay was not performed the box is grey filled. Results are reported as positive (P) or negative (N) according to the final assay thresholds. No donors had confirmed SARS-CoV-2 infection. Instances of close contact exposure with a confirmed infected individual were documented.

					post-V1				post-V2
Donor ID	Age (Years)	Sex	Vaccine	History of SARS-CoV-2 exposure	Days after vaccination	Anti-spike IgG/A/M	ELISpot response to spike pools	Whole Blood assay response to S1/S2	Days after vaccination	Anti-spike IgG/A/M	ELISpot response to spike pools	Whole Blood assay response to S1/S2
M001	35.0	F	Moderna						72	P	P	P
M002	39.7	F	Moderna		20	P	P	P	59	P	P
M003	35.6	F	Moderna		22	P	P	P	64	P	P	P
M004	35.3	M	Moderna		30	P	N	P	51	P	P	P
M005	24.9	M	Moderna		20	P	P	P	61	P	P
M007	36.2	M	Moderna		26	P	P	P	65	P	P
M008	23.0	F	Moderna	Close contact exposure with confirmed case	21	P	P	P	53	P	P	P
M009	27.6	F	Moderna		23	P	P	P	64	P	P
M010	33.3	F	Moderna						44	P	P	P
M011	45.0	F	Moderna						38	P	P	P
M012	50.8	M	Moderna						46	P	P	P
M013	25.8	M	Moderna		18	P	P	P	59	P	P	P
M014	23.4	M	Moderna	Close contact exposure with confirmed case	20	P	P	P	57	P	P	P
M017	50.5	F	Moderna		27	P	N	N	56	P	P
M018	61.6	F	Moderna		30	P	P
M019	26.2	M	Moderna						57	N	P
M020	61.0	F	Moderna						70	P	P	P
M021	38.5	F	Moderna						204	P	P	P
M022	27.7	M	Moderna						69	P	P
P000	63.7	F	Pfizer						45		P
P001	33.9	M	Pfizer						41	P	P	P
P002	59.6	M	Pfizer		24	N	P	P	60	P	P	P
P003	60.0	M	Pfizer						46	P	P	P
P004	59.0	F	Pfizer		21	P	N	P	55	P	P
P006	27.7	M	Pfizer						70	P	P
P007	29.0	M	Pfizer						69		P
P008	73.3	M	Pfizer						91	P	P	P
P009	81.0	F	Pfizer						63	P	P
P010	38.2	M	Pfizer						55	P	P
P012	34.9	M	Pfizer						55	P	P	P