Table 5.

Independent predictors at admission of the need for mechanical ventilation in the multivariate Cox proportional hazards model

	Unadjusted			Adjusted
	HR	95% CI	P	HR	95% CI	P
Inflammation score
Mild	Reference			Reference
Moderate	3.42	1.04 to 11.23	0.042	3.09	0.92 to 10.34	0.067
Severe	5.52	2.18 to 13.99	< 0.001	4.12	1.59 to 10.70	0.004
Age	1.02	0.99 to 1.04	0.072
Male gender	1.30	0.69 to 2.44	0.403
BMI	1.01	0.96 to 1.07	0.540
SaO2%, at admission	0.97	0.96 to 0.99	0.023
Charlson Comorbidity Index
1 point	0.92	0.37 to 2.31	0.870
2 points	1.28	0.46 to 3.53	0.631
3 points	1.62	00.67 to 3.86	0.272
4 points	1.25	0.45 to 3.62	0.678
5 points	1.31	0.45 to 3.79	0.611
6 points	2.27	0.28 to 18.30	0.433
Lymphocyte count	0.93	0.72 to 1.20	0.584
D-dimer
1st tercile (0–246 ng/mL)	Reference			Reference
2nd tercile (247–574 ng/mL)	2.61	1.14 to 5.97	0.023	2.24	0.95 to 5.26	0.063
3rd tercile (> 574 ng/mL)	5.44	4.44 to 12.14	< 0.001	3.01	1.28 to 7.05	0.011
Ferritin
1st tercile (0–356 μg/L)	Reference
2nd tercile (356–875 μg/L)	1.78	0.86 to 3.68	0.116
3rd tercile (> 875 μg/L)	2.39	1.18 to 4.85	0.016
Troponin I
1st tercile (0–6.6 ng/mL)	Reference			Reference
2nd tercile (6.7–24 ng/mL)	2.46	1.08 to 5.60	0.032	2.42	1.04 to 5.60	0.039
3rd tercile (> 24 ng/mL)	4.19	1.88 to 9.35	< 0.001	2.69	1.06 to 6.82	0.037
Interleukin-6
1st tercile (0–4.4 pg/ml)	Reference
2nd tercile (4.5–38.8 pg/ml)	1.74	0.84 to 3.60	0.134
3rd tercile (> 38.8 pg/ml)	2.03	1.09 to 3.76	0.025

Definitions: HR, hazard ratio; 95% CI, 95% confidence intervals; BMI, body mass index; SaO₂, oxygen saturation

Significant P values are in bold