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. 2021 Apr 26;12:587518. doi: 10.3389/fendo.2021.587518

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Copyright © 2021 Fröhlich and Wahl

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of treatments, pathologies and targets of action with stimulated processes by TH. Tissues relevant for the review are shown and other target tissues like bone, brain, kidney, gastrointestinal tract not represented. Established treatments are written in red, compounds/applications in clinical trials in turquoise. Pathologies and affected tissues are marked by symbols for the compounds (triangles for T3 and T4, squares for Resmetirom and VK2809, circles for 3-T1AM, and rosettes for Tetrac).