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. 2021 Apr 26;12:587518. doi: 10.3389/fendo.2021.587518

Table 1.

Overview of studies on prevalence and relevance of thyroid dysregulation in COVID-19.

Number of COVID-19 patients in the study Patients with abnormal TH values (%) Focus of the study Type of alterations in TH levels; control groups Reference
191 13.1 Specificity of TH level changes for COVID-19 TSH decreased (5.2%); fT3 decreased (5.2%); COVID-19 vs non-COVID-19 hospitalized patients (44)
334 13.7 Specificity of TH level changes for COVID-19 TSH and fT4 decreased; COVID-19 vs non-COVID-19 hospitalized patients (45)
52 21 Role of TH levels for the severity of COVID-19 TSH decreased and T4 increased (15%); critically ill COVID-19 vs critically ill non-COVID-19 patients (46)
60 35 Role of TH levels for the severity of COVID-19 TSH and T3 decreased (18.3%); TSH decreased and T4 increased (9.1%); critically ill vs non-severe COVID-19 (47)
50 58 Specificity of TH level changes for COVID-19 TSH and total T3 decreased and T4 normal; COVID-19 vs non-COVID-19 pneumonia and healthy individuals (48)
84 61.9 Specificity of TH level changes for COVID-19 TSH and total T3 decreased; COVID-19 vs non-COVID-19 pneumonia and healthy individuals (49)
48 75 Specificity of TH level changes for COVID-19 TSH and total T4 increased, total T3 decreased; COVID-19 pneumonia vs non-COVID-19 pneumonia (50)
100 na Role of TH levels for the severity of COVID-19 TSH and fT3 decreased; critically ill vs to non-severe COVID-19 (51)
113 na Role of TH levels for the severity of COVID-19 TSH and fT3 decreased: deceased COVID-19 vs survivors (52)