Table 4.
Liver and spleen volumes stratified by baseline complications of portal hypertensions*
| Variables | Hepatic encephalopathy | Esophageal varices | Ascites | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Yes (N = 120) | No (N= 274) | p-value | Yes (N=142) | No (N=248) | p-value | Yes (N=89) | No (N=285) | p-value | |
| Liver volume without bodyweight adjustment | |||||||||
| Total liver volume (TLV, cm3) | 1509.9±515.7 | 1695.0±617.7 | 0.002 | 1622.3±564.3 | 1651.1±614.3 | 0.63 | 1598.3±564.3 | 1665.8±591.7 | 0.33 |
| Functional liver volume (FLV, cm3) | 1481.4±488.6 | 1638.4±604.9 | 0.007 | 1580.4±548.6 | 1599.4±595.0 | 0.74 | 1550.9±553.0 | 1617.2±571.4 | 0.32 |
| Segment 1 (cm3) | 44.9±41.1 | 51.6±45.5 | 0.17 | 48.2±42.0 | 50.8±51.4 | 0.60 | 42.8±40.4 | 52.4±50.2 | 0.07 |
| Segment 2 (cm3) | 253.9±130.5 | 263.0±237.2 | 0.62 | 256.9±111.3 | 262.3±251.8 | 0.77 | 245.0±122.7 | 259.2±231.2 | 0.45 |
| Segment 3 (cm3) | 158.5±99.6 | 192.5±161.4 | 0.01 | 173.9±113.6 | 186.8±162.8 | 0.36 | 170.3±113.8 | 189.2±152.8 | 0.21 |
| Segment 4 (cm3) | 234.1±170.0 | 270.2±147.0 | 0.04 | 250.0±137.5 | 264.8±165.2 | 0.34 | 253.9±128.3 | 257.8±158.8 | 0.81 |
| Segment 5 (cm3) | 209.7±117.5 | 241.6±161.5 | 0.02 | 226.6±140.1 | 234.5±155.0 | 0.60 | 236.3±148.8 | 232.8±154.1 | 0.84 |
| Segment 6 (cm3) | 150.6±132.6 | 173.5±170.4 | 0.15 | 167.3±207.9 | 167.1±125.8 | 0.98 | 140.6±103.2 | 179.6±174.4 | 0.01 |
| Segment 7 (cm3) | 232.5±93.9 | 246.6±130.3 | 0.22 | 233.5±110.8 | 248.6±125.5 | 0.22 | 235.8±113.5 | 251.9±124.0 | 0.25 |
| Segment 8 (cm3) | 216.5±103.5 | 227.7±106.1 | 0.32 | 217.1±106.0 | 229.3±105.3 | 0.27 | 227.5±103.2 | 228.3±107.1 | 0.95 |
| Liver volume with bodyweight adjustment | |||||||||
| TLV:BW (cm3:kg) | 17.8±7.0 | 20.7±9.9 | 0.0009 | 19.3±6.8 | 20.3±10.4 | 0.25 | 20.5±13.2 | 19.3±7.2 | 0.40 |
| FLV:BW (cm3:kg) | 17.5±6.8 | 20.0±9.6 | 0.002 | 18.8±6.5 | 19.6±10.1 | 0.32 | 19.9±12.8 | 18.7±6.9 | 0.41 |
| Segment 1:BW (cm3/kg) | 0.5±0.4 | 0.6±0.6 | 0.04 | 0.6±0.5 | 0.6±0.6 | 0.38 | 0.5±0.5 | 0.6±0.6 | 0.26 |
| Segment 2:BW (cm3/kg) | 3.0±1.9 | 3.2±2.6 | 0.51 | 3.1±1.5 | 3.2±2.8 | 0.66 | 3.2±2.6 | 3.0±2.2 | 0.51 |
| Segment 3:BW (cm3/kg) | 1.9±1.4 | 2.4±2.2 | 0.01 | 2.1±1.4 | 2.3±2.3 | 0.22 | 2.3±2.4 | 2.2±1.8 | 0.79 |
| Segment 4:BW (cm3/kg) | 2.7±1.9 | 3.3±2.1 | 0.005 | 3.0±1.8 | 3.2±2.2 | 0.26 | 3.3±2.4 | 3.0±1.9 | 0.35 |
| Segment 5:BW (cm3/kg) | 2.4±1.3 | 2.9±2.0 | 0.005 | 2.7±1.6 | 2.9±2.0 | 0.36 | 3.0±2.3 | 2.7±1.7 | 0.22 |
| Segment 6:BW (cm3/kg) | 1.8±1.8 | 2.1±1.8 | 0.149 | 1.9±1.9 | 2.1±1.8 | 0.47 | 1.8±1.5 | 2.1±1.8 | 0.11 |
| Segment 7:BW (cm3/kg) | 2.8±1.2 | 3.0±1.9 | 0.07 | 2.8±1.3 | 3.1±1.9 | 0.07 | 3.0±2.0 | 2.9±1.5 | 0.66 |
| Segment 8:BW (cm3/kg) | 2.5±1.1 | 2.7±1.4 | 0.07 | 2.5±1.2 | 2.8±1.5 | 0.10 | 2.8±1.6 | 2.6±1.3 | 0.31 |
| Spleen volume with and without body weight adjustment | |||||||||
| Total spleen volume (cm3) | 800.5±481.5 | 754.5±522.4 | 0.39 | 893.9±521.2 | 683.7±457.1 | <0.0001 | 813.8±503.7 | 764.9±515.1 | 0.42 |
| Functional spleen volume (cm3) | 777.7±469.5 | 730.8±505.7 | 0.37 | 868.2±509.0 | 661.4±440.2 | <0.0001 | 788.5±487.5 | 742.4±501.0 | 0.44 |
| Total spleen volume:BW (cm3/kg) | 9.1±5.3 | 9.1±7.6 | 0.91 | 10.4±5.9 | 8.2±7.4 | 0.001 | 10.5±10.5 | 8.6±5.6 | 0.09 |
| Functional spleen volume:BW (cm3/kg) | 8.9±5.1 | 8.8±7.4 | 0.88 | 10.1±5.7 | 8.0±7.2 | 0.001 | 10.2±10.1 | 8.3±5.4 | 0.10 |
| Total liver to spleen ratio | 3.0±4.3 | 3.5±3.2 | 0.22 | 2.4±1.5 | 3.9±4.2 | 0.26 | 2.7±1.9 | 3.5±3.9 | 0.01 |
| Functional liver to spleen ratio | 3.0±4.3 | 3.5±3.1 | 0.29 | 2.4±1.5 | 3.9±4.2 | <0.0001 | 2.7±1.9 | 3.5±3.9 | 0.008 |
*
only reported cases with available data on the complications of portal hypertension