Table II.
Parameter (Mean± SEM) | Baseline | 12 Months | p Value |
---|---|---|---|
Glycohemoglobin A1c (%) | 9.5±0.4 | 8.3±0.4 | 0.01 |
Advanced glycated end products (units) | 12.1±2.2 | 7.4±1.2 | 0.03 |
Serum creatinine (mg/dL) | 1.8±0.1 | 2.0±0.2 | 0.03 |
Creatinine clearance (mL/min) | 55±3 | 50±5.0 | 0.20 |
Hemoglobin (g/dL) | 13.5±0.4 | 12.2±0.4 | 0.01 |
Hematocrit (%) | 39.5±1.4 | 36.6±1.3 | 0.01 |
Systolic blood pressure (mm Hg) | 140±3 | 141±2 | 0.64 |
Diastolic blood pressure (mm Hg) | 81±2 | 81±1 | 0.93 |
Mean arterial pressure (mm Hg) | 100±2 | 101±2 | 0.60 |
Weight (kg) | 72.8±2.5 | 72.8±2.9 | 1.00 |