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Adjusted Mean Change in Pulse Pressure* (±SE) From Baseline to Weeks 2, 4, and 8
| Week 2 | Week 4 | Week 8 | |
|---|---|---|---|
| Placebo (n=50) | –2.1±1.23 | 0.9±1.23 | 0.8±1.38 |
| Eplerenone 50 mg q.d. (n=48) | –2.4±1.25 | –2.1±1.24 | –1.4±1.39 |
| Eplerenone 100 mg q.d. (n=46) | –3.2±1.29 | –2.8±1.28† | –2.7±1.44 |
| Eplerenone 200 mg q.d. (n=48) | –4.8±1.24 | –4.4±1.24ɛ | –3.2±1.39ɛ |
| *pulse pressure=systolic blood pressure–diastolic blood pressure; † p=0.0182; ɛ p≤0.0163 | |||
