Table II.

 Effects of Angiotensin‐Converting Enzyme Inhibitors (ACEIs) on Carotid—Femoral Pulse Wave Velocity (PWV) in Randomized Clinical Trials

						ΔMAP (mm Hg)		ΔMAP (%)		ΔPWV (m/s)		ΔPWV (%)
Study	Design	Duration (wk)	N	ACEI	C	ACEI	C	ACEI	C	ACEI	C	ACEI	C
Mahmud et al., 2002 23	Crossover	4	12	Captopril	Valsartan	−15	−16.3	−12.7	−14	−0.8	−0.8	−7.2	−7.2
Rajzer et al., 2003 24	Parallel	24	62	Quinapril	Losartan	−21	−14.7	−18.1	−13.1	−1.7	−0.2	−15	−2
Rajzer et al., 2003 24	Parallel	24	75	Quinapril	Amlodipine	−21	−15	−18.1	−13.4	−1.7	−0.6	−15	−5.1
C=control drug; Δ=change; MAp=mean arterial pressure