Table IV.

Metabolic Syndrome—Pharmacologic Interventions

Abnormality	Treatment Options
Hypertension	Angiotensin‐converting enzyme inhibitor or angiotensin receptor blocker initial therapy, adding calcium channel blocker* or lowdose thiazide as needed
Dyslipidemia	Statin or fibrate or combination; fibrate preferred for triglycerides >500 mg/dL
Glucose intolerance	Metformin, thiazolidinedione, or combination; avoid insulin if at all possible
Prothrombotic state	Aspirin
*Nondihydropyridine preferred if microalbuminuria or proteinuria present