Figure 4.

Cardiovascular regulation occurs with the interaction of the sympathetic nervous system (SNS) and the renin‐angiotensin system (RAS) with the vascular endothelium. AT indicates angiotensin II type 1 receptor; ET, endothelin; AT II, angiotensin II; ACEI, angiotensin‐converting enzyme inhibitor; Ach, acetylcholine; M, muscarinergic receptor; ET_B, endothelin B receptor; ARB, angiotensin receptor blocker; NO, nitric oxide; PGI₂, prostacyclin; ET_A, endothelin A receptor; and Bβ₂, bradykinin receptor. Reproduced with permission from Wenzel et al. ¹⁰⁵