Table IV.
Cox Regression Model Applied to Persistence With Treatment
| Factor | p Value | Hazard Ratio (95% CI)* |
|---|---|---|
| Age | <0.0001 | 0.978† (0.976–0.979) |
| Cardiac disease (present) | 0.0002 | 1.666 (1.270–2.185) |
| Diabetes (present) | 0.0002 | 1.394 (1.171–1.658) |
| Previous CV hospital admissions (present) | <0.0001 | 1.507 (1.369–1.658) |
| Patients with two or more | <0.0001 | 1.630 (1.341–1.981) |
| comorbidities (present) | ||
| Drug class at enrollment | ||
| AIIAs | <0.0001 | —— |
| ACE inhibitors | <0.0001 | 1.386 (1.250–1.538) |
| CCBs | <0.0001 | 1.663 (1.499–1.846) |
| Diuretics | <0.0001 | 1.853 (1.670–2.056) |
| CI=confidence interval; CV=cardiovascular; AIIAs=angiotensin II receptor antagonists; ACE=angiotensin‐converting enzyme; CCBs=calcium channel blockers *figures in parentheses indicate the reference category of categorical variables (hazard ratio=1), hazard ratio is adjusted for other variables in the table, global χ 2 =1841.451, p<0.0001; †related to 1‐year age increment | ||