Table VI.

Multiple Linear Regression Analysis of Cost of Drug Treatment

Factor	Reference Category	Regression Coefficient (b)	95% CI	p Value
Age		−0.43*	(−0.81 to −0.05)	0.027
Compliance pattern	Increased cost compared
	with patients who stayed
	on initial therapy
Combining the class at		26.35	(11.37–41.34)	0.001
enrollment
Switching the class at	33.17	(18.65–47.70)	<0.001
enrollment
No. of different classes		10.94†	(2.62–19.27)	0.010
Class at enrollment	Increased cost compared
	with diuretics
β Blockers		67.45	(49.71–85.20)	<0.001
CCBs		188.84	(172.81–204.87)	<0.001
ACE inhibitors		168.20	(153.05–183.35)	<0.001
AIIAs		278.19	(258.84–297.54)	<0.001
CI=confidence interval; CCBs=calcium channel blockers; ACE=angiotensin‐converting enzyme; AIIAs=angiotensin II receptor antagonist; *related to 1‐year age increment; †related to one unit increment