Table III.

Effects of Diuretics on Cholesterol Levels in Controlled Clinical Trials

Berglund & Anderson
6 Yr	−12
MRC Trial
3 + Yr
Men/Women—Rx/Pl	0/‐1/‐5–4
MAPHY
6 Yr	−1
HDFP
4 Yr (SI)
High doses diuretics	−9
Oslo
4 Yr
Active Rx/control	+1/+2
MRFIT
6 Yr
(SI) (UC)	−18/−14
MRC=Medical Research Council study; MAPHY=Metoprolol Atherosclerosis Prevention in Hypertension; HDFP=Hypertension Detection and Follow‐up Program; MRFIT=Multiple Risk Factor Intervention Trial; Pl=placebo; C=care; SI=special intervention; UC=usual care