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Mean Change in Blood Pressure From Baseline (mm Hg)
| Therapy | 4 Weeks | 8 Weeks |
|---|---|---|
| Monotherapy (n=44) | ||
| SBP/enalapril | −0.1 | −4.8* |
| DBP/enalapril | −5.7* | −4.4* |
| SBP/candesartan | 1.4 | −4.7* |
| DBP/candesartan | −2.9 | −5.6** |
| Combination therapy (n=18) | ||
| SBP/enalapril + candesartan | 5.1 | 1.3 |
| DBP/enalapril + candesartan | −1.1 | −1.2 |
| SBP=systolic blood pressure; DBP=diastolic blood pressure; *p<0.01 compared with placebo; **p<0.04 compared with enalapril | ||
