Table I.
Criteria for Allocation Into Cardiovascular (CV) Risk Categories and Recommended Blood Pressure (BP) and Low‐Density Lipoprotein Cholesterol (LDL‐C) Target Levels for Each Risk Group
| CV Risk Group | |||
|---|---|---|---|
| I | II | III | |
| CV risk factors* | HTN + DYS; no additional CV risk factors | HTN + DYS with ≥1 additional CV risk factor, excluding CHD and DM | HTN + DYS + CHD, DM, or other atherosclerotic disease |
| Entry criteria** | |||
| BP (mm Hg) | SBP 140–179 and/or DBP 90–109 | SBP 140–179 and/or DBP 90–109 | SBP 130–159 and/or DBP 85–99 |
| Fasting LDL‐C (mg/dL [mmol/L]) | 161–250 (4.1–6.5) | 131–250 (3.4–6.5) | 101–250 (2.6–6.5) |
| Treatment goals | |||
| BP (mm Hg)† | <140/90 | <140/90 | <130/85 |
| LDL‐C†† (mg/dL [mmol/L]) | <160(<4.1) | <130(<3.4) | <100(<2.6) |
| HTN=hypertension; DYS=dyslipidemia; DM=diabetes mellitus; SBP=systolic BP; DBP=diastolic BP; *includes: age ≥45 yr (male) or ≥55 yr (female), history of coronary heart disease (CHD) in parent or sibling before age 55 yr (male) or 65 yr (female), smoking (current), high‐density lipoprotein cholesterol (HDL‐C) <40 mg/dL. Patients with HDL‐C ≥60 mg/dL required two additional CV risk factors; **average of measurements collected at two or three visits 7–14 days apart; †defined according to the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, 39 except for group III patients, who were at lower goals for the purpose of this study; ††defined according to National Cholesterol Education Program Adult Treatment Panel III 15 | |||