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. 2007 Jan 31;8(8):571–583. doi: 10.1111/j.1524-6175.2006.05636.x

Table III.

Least Square Mean Percentage Changes (+ Standard Error) From Baseline in Lipid Parameters of Entire Study Population (Risk Groups I, II, and III Combined)

Double‐Blind Treatment Group*
Lipid Parameter AML 5 mg+
ATV 10 mg AML 5 mg ATV 10 mg Placebo Single‐Blind,
Open‐Label**
LDL‐C −37.2±0.9†,†† −1.8±0.9 −33.9±0.9 0.2±0.8 −41.0±0.4
Patients (n) 201 193 193 229 687
Total cholesterol −27.7±0.6‡‡†† −2.1±0.6 −24.4±0.6 −0.9±0.6 −31.0±0.4
Patients (n) 201 193 193 229 687
Triglycerides −23.0*±2.2†† −2.3±2.3 −17.2±23 −0.1±2.1 −29.0±1.1
Patients (n) 201 193 193 229 687
HDL‐C 5.0±1.0†† 0.0±1.0 4.1±1.0§ 0.2±0.9 5.2±0.6
Patients (n) 201 193 193 229 687
Apolipoprotein B −30.7±0.8§§†† −1.7±0.8 −27.9±0.8 −1.0±0.7 −34.5±0.4
Patients (n) 189 185 183 210 687
LDL‐C=low‐density lipoprotein cholesterol; HDL‐C=high‐density lipoprotein cholesterol; *from baseline to the end of the doubleblind phase (Week 8); **from baseline to the end of the open‐label phase (Week 28); p=0.007 vs. atorvastatin alone; †† p<0.001 vs. amlodipine alone; p<0.001 vs. placebo; ‡‡ p<.001 vs. atorvastatin alone; § p=0.005 vs. placebo; §§ p=0.013 vs. atorvastatin alone