Figure 10.

Radionuclide angiography is a highly reproducible method for determining ejection fraction for patients in a sinus rhythm. The top panel shows a background‐corrected time‐activity curve over a cardiac cycle. The bottom panel shows the first derivative of those counts: diastolic function is determined by evaluating the time‐activity curves during diastole; time‐to‐peak filling rate (TPFR) and the peak‐filling rate (PFR) are calculated as measures of diastolic dysfunction. dv/dt=the derivitave of ventricular volume over time; EDV=end‐diastolic volume