Fig 6. Frequency distribution of ATAC-seq DNA read lengths during HSV infection.

The frequency distribution of sequenced fragment lengths of reads that aligned to the human genome in Control (A) and ATRX-KO (B) cells infected with an ICP0- HSV at MOI 5 and harvested at 4 hpi. (C) The frequency distribution of sequenced fragment lengths of reads that aligned to the HSV genome in proteinase K treated, purified HSV (WT) DNA. The frequency distribution of sequenced fragment lengths of reads that aligned to the HSV genome in Control (D) and ATRX-KO (E) cells infected with an ICP0- HSV at MOI 5 and harvested at 1, 4, and 8 hpi. Data shown in Fig 6 is representative of 2 independent experiments.