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. 2021 May 10;18(5):e1003602. doi: 10.1371/journal.pmed.1003602

Table 3. Subgroup results for the effect of parenting interventions on parenting outcomes stratified by study characteristics.

Parenting knowledge Parenting practices Parent–child interactions Parental depressive symptoms
Moderator N SMD (95% CI) P value N SMD (95% CI) P value N SMD (95% CI) P value N SMD (95% CI) P value
Country economic grouping
High-income countries 5 0.45 (0.10, 0.80) 0.51 15 0.08 (−0.01, 0.16) <0.001 22 0.38 (0.20, 0.55) 0.52 12 −0.02 (−0.09, 0.05) 0.13
Low- and middle-income countries 11 0.60 (0.30, 0.90) 20 0.47 (0.34, 0.61) 5 0.47 (0.25, 0.69) 12 −0.13 (−0.27, 0.01)
Child age at baseline
<12 months 8 0.48 (0.26, 0.70) 0.55 21 0.23 (0.11, 0.35) 0.27 18 0.29 (0.16, 0.42) 0.14 16 −0.03 (−0.13, 0.07) 0.47
≥12 months 8 0.62 (0.21, 1.04) 14 0.47 (0.29, 0.66) 9 0.59 (0.22, 0.96) 8 −0.16 (−0.32, 0.01)
Intervention content
Responsive caregiving 11 0.68 (0.39, 0.97) 0.001 24 0.42 (0.29, 0.56) 0.001 22 0.47 (0.30, 0.64) <0.001 18 −0.08 (−0.18, 0.01) 0.82
No responsive caregiving 5 0.19 (0.13, 0.26) 11 0.11 (0.01, 0.22) 5 0.05 (−0.01, 0.12) 6 −0.07 (−0.34, 0.21)
Intervention duration
<12 months 6 0.57 (0.32, 0.82) 0.92 11 0.51 (0.30, 0.72) 0.01 14 0.44 (0.23, 0.65) 0.05 10 −0.13 (−0.32, 0.07) 0.27
≥12 months 10 0.54 (0.20, 0.89) 24 0.25 (0.13, 0.37) 13 0.33 (0.13, 0.53) 14 −0.05 (−0.14, 0.04)
Delivery
Individual only 8 0.46 (0.18, 0.75) 0.92 15 0.24 (0.12, 0.35) 0.14 15 0.32 (0.17, 0.48) 0.67 12 −0.08 (−0.17, 0.01) 0.14
Group only - - 6 0.42 (0.16, 0.68) 4 0.65 (−0.07, 1.37) 4 −0.22 (−0.83, 0.39)
Individual and Group 7 0.48 (0.25, 0.72) 14 0.38 (0.15, 0.60) 8 0.36 (0.10, 0.62) 8 0.02 (−0.13, 0.17)
Setting
Home visiting only 7 0.39 (0.11, 0.68) 0.64 12 0.27 (0.15, 0.38) 0.65 16 0.35 (0.19, 0.51) 0.50 12 −0.07 (−0.17, 0.02) 0.67
Community only - - 5 0.32 (0.16, 0.48) 4 0.65 (−0.07, 1.37) 3 −0.17 (−1.39, 1.04)
Clinic only - - 6 0.33 (−0.01, 0.67) - - 4 −0.10 (−0.43, 0.22)
Combination 6 0.49 (0.21, 0.77) 12 0.39 (0.11, 0.65) 6 0.24 (0.00, 0.48) 5 −0.01 (−0.27, 0.24)
Study quality
Lower risk of bias (<6) 13 0.60 (0.34, 0.87) 0.48 27 0.37 (0.25, 0.50) 0.06 18 0.36 (0.22, 0.51) 0.08 19 −0.10 (−0.20, 0.01) 0.39
Higher risk of bias (≥6) 3 0.33 (−0.10, 0.76) 8 0.12 (−0.04, 0.28) 9 0.47 (0.09, 0.85) 5 −0.02 (−0.24, 0.20)

N = number of RCTs represented in subgroup analysis. SMD, standardized mean difference. P value corresponds to test of subgroup differences. Bolded values indicate significant moderator effects (P < 0.05). Empty cells represent cases in which there were two or fewer studies for a given subgroup.