Table I.
Meta‐Analysis | No. of Trials | Intervention | Average Duration | Mean BP Lowering (SBP/DBP), mm Hg | 95% CI |
---|---|---|---|---|---|
Cappucio, 1991 25 | 19 | 100 mmol/d diet; 48–120 mmol/d KCl; 66 mmol/d K Glu +Cit | 39 d | 5.9/3.4 | −6.6 to –5.2 |
−4.0 to 2.8 | |||||
Whelton, 1997 26 | 33 | 100–200 mmol/d diet; 60–120 mmol/d Kcl; 120 mmol/d K Cit + Bicarb | 5 wk | 3.1/2.0 | −1.9 to –4.3 |
−0.5 to –3.4 | |||||
Geleijnse, 2003 27 | 27 | 44 mmol (1.7 g) (form not given) | >2 wk | 2.4/1.6 | −3.8 to –1.0 |
−2.7 to –0.5 | |||||
Dickinson, 2006 28 | 5 | >100 mmol/d diet; 48–120 mmol/d Kcl; 120 mmol/d K Cit + Bicarb | >8 wk | 11.2/5.0 | −25.2 to 2.7 |
−12.5 to 2.4 | |||||
Abbreviations: BP, blood pressure; CI, confidence interval; DBP, diastolic blood pressure; SBP, systolic blood pressure. Forms of K+ include Kcl, citrate (Cit), gluconate (Glu), and bicarbonate (Bicarb). One Meq or mmol of K+ equals 39.09 mg. |