Figure 4.

Changes from baseline in (a) trough mean sitting diastolic blood pressure (DBP) and (b) trough mean sitting systolic blood pressure (SBP) at end point after treatment with aliskiren monotherapy. Graph shows least‐squares mean changes from baseline in patients receiving treatment with placebo (open bars) or monotherapy with aliskiren 75, 150, or 300 mg once daily (filled bars). Data are presented as the least‐squares mean ± standard error of the mean. Reprinted with permission from Pool et al. ²⁶