Table.
Effects of Antihypertensive Agents on Targets of the RAS Pathway
| Angiotensin I | Angiotensin II | Renin Concentration | Plasma Renin Activity | |
|---|---|---|---|---|
| Direct renin inhibitors | ↓ | ↓ | ↑ | ↓ | 
| Angiotensin receptor blockers | ↑ | ↑ | ↑ | ↑ | 
| Angiotensin‐converting enzyme inhibitors | ↑ | ↓ | ↑ | ↑ | 
| Abbreviation: RAS, renin‐angiotensin system. ↓ decreased; ↑ increased. Adapted with permission from Brown. 7 | ||||