Table IV.

Blood Pressure Change from Baseline by Age at Week 4

Ibuprofen Substudy	Total No.	CFB, LSM	Total No.	CFB, LSM	P Value
	Lumiracoxib 400 mg Once Daily		Ibuprofen 800 mg 3 Times Daily
Systolic blood pressure
Age, y
≤64	2471	0.73	2475	3.28	<.0001
65–74	1362	0.35	1361	3.01	<.0001
≥75	459	0.38	466	2.65	.0190
Diastolic blood pressure
Age, y
≤64	2470	0.12	2475	1.10	<.0001
65–74	1362	0.17	1361	1.22	.0006
≥75	459	−0.51	466	0.17	.1927
Naproxen Substudy	Lumiracoxib 400 mg Once Daily		Naproxen 500 mg Twice Daily
Systolic blood pressure
Age, y
≤64	2566	0.90	2577	1.97	.0027
65–74	1589	−0.22	1545	1.53	.0002
≥75	500	0.08	506	1.88	.0475
Diastolic blood pressure
Age, y
≤64	2566	0.23	2577	0.74	.0164
65–74 years	1589	−0.25	1545	−0.04	.4447
≥75	500	−0.55	506	0.25	.1196
Abbreviations: CFB, change from baseline; LSM, least‐squares mean.