Table I.
Variable Effects of Lipid‐Lowering Drugsa
Lipid‐Lowering Class | LDL‐C Reductions | Triglyceride Reductions | HDL‐C Increases |
---|---|---|---|
Fibrates, % | 5–20 | 20–50 | 10–20 |
Bile acid sequestrants, % | 15–30 | No effects | 3–5 |
Niacin, % | 5–25 | 20–50 | 15–35 |
Ezetimibe, % | 18 | 8b | 1 |
Statins, % | 18–55 | 7–30 | 5–15 |
Percentages are mean change from baseline except where marked. Abbreviations: HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol. aModified from Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. 2 bMedian percentage change from baseline. |