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. 2007 Dec 19;9(Suppl 12):23–30. doi: 10.1111/j.1524-6175.2007.07805.x

Table II.

Effect of Age, Obesity, and Type 2 Diabetes Status on Mean SeSBP Following 7 to 8 Weeks' Fixed‐Dose Irbesartan/Hydrochlorothiazide 300/25 mg in Pooled Hypertensive Patientsa

Patient subgroup Baseline, No. SeSBP Adjusted Mean Change From Baseline
Mean (SD) Difference P Value 95% CI
Age
 65 y or older 121 −24.6 (1.5) −3.6 .015 −6.4 to –0.7
 Younger than 65 y 675 −21.0 (1.8)
Obesity
 BMI ≥30 kg/m2 378 −22.9 (1.6)
 BMI <30 kg/m2 414 −22.7 (1.5) −0.2 .826 −2.3 to 1.8
Type 2 diabetes
 With type 2 diabetes 99 –21.4 (1.9)
 Without type 2 diabetes 697 −24.1 (1.5) 2.7 .082 −0.3 to 5.8
aData were adjusted using an analysis of covariance model, for baseline age, body mass index (BMI), type 2 diabetes, sex, race, cholesterol, target organ damage, and acute coronary syndrome. Abbreviations: CI, confidence interval; SeSBP, seated systolic blood pressure.