Table II.
Open Label | Randomized | ||
---|---|---|---|
Quinapril 20 mg (n=374) | Quinapril 40 mg (n=167) | Quinapril 20 mg+ Amlodipine Besylate 5 mg (n=162) | |
Any concomitant drugs, No. (%) | 338 (90.4) | 149 (89.2) | 142 (87.7) |
Antidiabetic | 218 (58.3) | 101 (60.5) | 93 (57.4) |
Antihyperlipidemia | 143 (38.2) | 62 (37.1) | 66 (40.7) |
Vasodilators | 41 (11.0) | 14 (8.4) | 21 (13.0) |
Cerebral | 4 (1.0) | 0 | 3 (1.9) |
Peripheral | 12 (3.2) | 6 (3.6) | 6 (3.7) |
Used in angina pectoris | 30 (8.0) | 10 (6.0) | 15 (9.3) |
Antiplatelet | 159 (42.5) | 81 (48.5) | 66 (40.7) |
Proportion of patients receiving antihypertensives before study entry, % | |||
≤2 antihypertensives | 73.4 | 82.6 | 78.4 |
≥3 antihypertensives | 26.7 | 17.3 | 21.6 |