Table 3.
Correlation between cfPWV and clinical variables among the CKD patients.
| Variables | Carotid-femoral pulse wave velocity (m/s) |
||||
|---|---|---|---|---|---|
| Simple regression |
Multivariable regression |
||||
| r | p | Beta | Adjusted R2 change | p | |
| Female | −0.123 | 0.127 | – | – | – |
| Diabetes mellitus | 0.236 | 0.003* | 0.177 | 0.026 | 0.011* |
| Hypertension | −0.041 | 0.611 | – | – | – |
| Glomerulonephritis | −0.093 | 0.250 | – | – | – |
| Smoking | −0.031 | 0.702 | |||
| Age (years) | 0.365 | <0.001* | 0.267 | 0.052 | <0.001* |
| Body mass index (kg/m2) | 0.103 | 0.201 | – | – | – |
| SBP (mmHg) | 0.365 | <0.001* | 0.283 | 0.094 | <0.001* |
| DBP (mmHg) | 0.139 | 0.086 | – | – | – |
| TCH (mg/dL) | −0.087 | 0.283 | – | – | – |
| Log-Triglyceride (mg/dL) | 0.018 | 0.821 | – | – | – |
| LDL-C (mg/dL) | −0.106 | 0.190 | – | – | – |
| Log-Glucose (mg/dL) | 0.119 | 0.140 | – | – | – |
| Log-BUN (mg/dL) | 0.203 | 0.011* | – | – | – |
| Log-Creatinine (mg/dL) | 0.245 | 0.002* | – | – | – |
| eGFR (mL/min) | −0.284 | <0.001* | – | – | – |
| Total calcium (mg/dL) | 0.025 | 0.754 | – | – | – |
| Phosphorus (mg/dL) | 0.002 | 0.977 | – | – | – |
| Log-Indoxyl sulfate (μg/mL) | 0.373 | <0.001* | 0.217 | 0.133 | 0.003* |
Data of triglyceride, glucose, BUN, creatinine, and indoxyl sulfate levels showed skewed distribution and therefore were log-transformed before analysis.
Analysis of data was done by univariate or multivariate stepwise linear regression analysis (adapted factors were diabetes mellitus, age, SBP, eGFR, and log-indoxyl sulfate).
SBP: systolic blood pressure; DBP: diastolic blood pressure; TCH: total cholesterol; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate.
*p < 0.05 was considered statistically significant.