Table 2.
Cardiopulmonary exercise test results
| All patients (n = 48) | Male (n = 36) | Female (n = 12) | p value | |
|---|---|---|---|---|
| SBPbasal (mmHg) | 129 ± 15 | 129 ± 15 | 126 ± 14 | 0.512 |
| SBPpeak (mmHg) | 189 ± 22 | 189 ± 24 | 180 ± 21 | 0.214 |
| RERpeak | 1.19 ± 0.08 | 1.18 ± 0.08 | 1.17 ± 0.09 | 0.738 |
| WRpeak (W) | 194 ± 52 | 206 ± 50 | 156 ± 40 | 0.004 |
| % predicted | 88 (82–94) | 88 (81–95) | 86 (71–102) | 0.787 |
| W/kg | 3.14 ± 0.64 | 3.25 ± 0.65 | 2.8 ± 0.47 | 0.022 |
| HRrest (bpm) | 82 ± 18 | 81 ± 17 | 87 ± 21 | 0.314 |
| HRpeak (bpm) | 187 [179–190] | 187 [179–190] | 187 ± 11 | 0.939 |
| % predicted | 101 (99–103) | 101 (98–103) | 100 (95–105) | 0.853 |
| HRreserve (bpm) | 103 ± 18 | 104 ± 17 | 99 ± 21 | 0.899 |
| HR01% | 31 ± 10 | 32 ± 11 | 30 ± 7 | 0.595 |
| HR02% | 49 ± 13 | 49 ± 14 | 51 ± 11 | 0.589 |
| VO2peak (ml/min) | 2289 ± 599 | 2424 ± 573 | 1656 ± 389 | < 0.001 |
| % predicted | 75 (72–77) | 74 (71–77) | 77 (70–84) | 0.358 |
| ≤ 84%, n(%) | 17 (36) | 12 (33) | 5 (42) | 0.601 |
| (ml/kg/min) | 37.1 ± 7.2 | 39.1 ± 6.7 | 31.2 ± 4.4 | < 0.001 |
| VE (VE/VCO2 slope) | 29.2 ± 3.6 | 28.8 ± 3.1 | 30.1 ± 4.6 | 0.273 |
| O2pulsemax (ml/bpm) | 12.3 ± 3.2 | 13.3 ± 3.0 | 9.1 ± 2.1 | < 0.001 |
| % predicted | 79 (73–84) | 86 (80–91) | 58 (49–67) | < 0.001 |
| OUES (ml/min/log(L/min)) | 2191 ± 553 | 2363 ± 502 | 1826 [1292–1923] | < 0.001 |
| % predicted | 82 (77–87) | 84 (78–89) | 77 (68–87) | 0.505 |
| ≤ 84%, n (%) | 27 (56) | 21 (58) | 6 (50) | 0.614 |
| OUES/kg | 36.5 ± 7.8 | 38.9 ± 7.6 | 32.1 ± 6.7 | 0.012 |
| OUES/BSA | 1283 ± 227 | 1353 ± 199 | 1073 ± 171 | < 0.001 |
Data shown as mean ± SD, median [IQR] or number (%). The % predicted values were shown as mean (95% CI)
HRpeak maximal heart rate at peak exercise, HRreserve maximal heart rate-resting heart rate, HRrest resting heart rate, HR01% percentage heart rate recovery at 1 min, HR02% percentage heart rate recovery at 2 min, O2pulsemax maximal O2 pulse, OUES oxygen uptake efficiency slope, RERpeak respiratory exchange ratio at peak exercise, SBPbasal systolic blood pressure at rest, SBPpeak systolic blood pressure at peak exercise, VO2peak oxygen uptake at peak exercise, VE ventilatory efficiency; WRpeak peak work rate