Table 1.
Demography and radioactivity data.
| Patients | Controls | P valuea | |
|---|---|---|---|
| Gender, n | |||
| Female | 13 | 13 | – |
| Male | 4 | 4 | – |
| Age, years (mean ± SD) | 47 ± 13 | 47 ± 14 | – |
| WAIS, matrix reasoningb (mean ± SD) | 12.4 ± 2.9 | 12.7 ± 3.2 | – |
| Current MDD episode duration, months | 15 ± 13 | – | – |
| Family history of MDD, n (%) | 7 (41%) | – | – |
| Prior MDD episodes, n (%) | |||
| 1–2 | 8 (47%) | – | – |
| >2 | 9 (53%) | – | – |
| Prior CBT, n (%) | 9 (53%) | – | – |
| Previous AD, n (%) | 9 (53%) | – | – |
| Time since AD, months (min–max) | 8–204 | – | – |
| Comorbid psychiatric diagnosisc, n (%) | 6 (35%) | – | – |
| Injected radioactivity, MBq (mean ± SD) | |||
| PET1 | 424 ± 82 | 408 ± 85 | 0.57 |
| PET2 | 406 ± 91 | – | 0.56 |
| Molar radioactivity, GBq/μmol (mean ± SD) | |||
| PET1 | 216 ± 65 | 231 ± 134 | 0.67 |
| PET2 | 200 ± 81 | – | 0.52 |
| Injected mass, μg (mean ± SD) | |||
| PET1 | 0.58 ± 0.19 | 0.93 ± 1.28 | 0.28 |
| PET2 | 0.68 ± 0.38 | – | 0.33 |
AD antidepressant, CBT Cognitive Behavioral Therapy, MDD major depressive disorder.
aCalculated using independent t test.
bRaw score standardized for age.
cGeneralized anxiety disorder; social anxiety disorder; panic disorder; hypochondriasis.