Table 2.
HLA-DQB1 protein levels in tumour and stroma related to clinicopathological characteristics for 389 cervical carcinoma cases with evaluable results.
| Variables (n)a | HLA-DQB1 protein levels | P valueb | |
|---|---|---|---|
| Low (n = 111) | High (n = 278) | ||
| Median age (n = 389) | 0.07 | ||
| ≤44 years | 45 (24) | 141 (76) | |
| >44 years | 66 (32) | 137 (68) | |
| FIGO-09 stage (n = 389) | <0.001 | ||
| I–IB1 | 57 (22) | 196 (78) | |
| IB2–IV | 54 (40) | 82 (60) | |
| Max tumour diameter (n = 231) | 0.04 | ||
| <4 cm | 30 (23) | 100 (77) | |
| ≥4 cm | 36 (36) | 65 (64) | |
| Histologic type (n = 389) | 0.08 | ||
| Squamous cell carcinoma | 80 (29) | 197 (71) | |
| Adenocarcinoma | 19 (22) | 66 (78) | |
| Other histologic type | 12 (44) | 15 (56) | |
| Histologic grade (n = 385) | 0.03 | ||
| Grade 1/2 | 86 (26) | 239 (74) | |
| Grade 3 | 24 (40) | 36 (60) | |
| Depth of invasion (n = 271) | 0.44 | ||
| Low (≤7 mm) | 28 (21) | 102 (79) | |
| High (>7 mm) | 36 (26) | 105 (74) | |
| Inflammatory reaction (n = 374) | 0.03 | ||
| No | 18 (39) | 28 (61) | |
| Intermediate | 83 (29) | 206 (71) | |
| Strong | 5 (13) | 34 (87) | |
| Vascular space invasion (n = 282) | 0.51 | ||
| No | 45 (23) | 148 (77) | |
| Yes | 24 (27) | 65 (73) | |
The number of cases in each group is given followed by percentage for each row within parentheses.
FIGO The Féderation Internationale de Gynécologie et d’Obstétrique.
Statistically significant p < 0.05 values are in bold.
an = number of cases with available data for each variable.
bPearson’s χ2 test.