Table 1.

Demographics of study population

	Opioid-exposed (n=29)	Controls (n=42)	p value
Male, n (%)	10 (34%)	20 (48%)	0.27
Gestational age at birth (weeks), mean (SD)	38.9 (1.1)	39.0 (0.72)	0.55
Birth weight (g), mean (SD)	3048 (299)	3274 (432)	0.02
Head circumference at birth (cm), mean (SD)	34.1 (1.3)	34.0 (1.4)	0.89
Postmenstrual age at scan (weeks), mean (SD)	44.7 (1.2)	44.0 (2.0)	0.07
Race/ethnicity			0.004
Non-Hispanic White	24	20
Non-Hispanic Black	4	20
Non-Hispanic Asian	0	1
Hispanic White	1	1
Maternal smoking, n (%)	25 (86%)	3 (7%)	<0.001
Reported maternal alcohol use during pregnancy	1 (3%)	1 (2%)	1.0
Maternal Hepatitis C, n (%)	19 (66%)	0 (0%)	<0.001
Maternal college degree, n (%)	5 (17%)	24 (57%)	0.001
Maternal methadone, n (%)	12 (41%)	n/a	n/a
Maternal buprenorphine, n (%)	15 (52%)	n/a	n/a
Maternal heroin and/or fentanyl, n (%)	12 (41%)	n/a	n/a
Neonatal abstinence syndrome requiring opioid treatment, n (%)	13 (45%)	n/a	n/a

Two-sided t-test was used to compare continuous variables and Fisher’s exact test was used to compare categorical variables.