Table 5.
Serum concentrations of discriminant biomolecules identified by gender-specific sequential and orthogonalized covariance selection (SO-CovSel) analysis
| Men (n = 75) | |||
|
PF&S (n = 25) |
NonPF&S (n = 50) |
||
| Matrix 1 | MIP-1β (ng/mL) | 144.0 (88.0) | 189.4 (58.4) |
| Matrix 4 | α-aminobutyric acid (μmol/L) | 18.7 (5.4) | 23.4 (6.1) |
| Asparagine (μmol/L) | 92.1 (14.3) | 76.6 (20.2) | |
| Aspartic acid (μmol/L) | 24.6 (14.3) | 16.4 (5.2) | |
| Phosphoetanolamine (μmol/L) | 0.9 (0.3) | 1.4 (0.8) | |
| Matrix 3 | CAF (ng/mL) | 0.2 (0.1) | 0.1 (0.1) |
| Hsp72 (ng/mL) | 1.3 (0.6) | 2.1 (1.5) | |
| Matrix 2 | FGF21 (ng/mL) | 535.2 (362.9) | 275.2 (340.9) |
| Women (n = 125) | |||
|
PF&S (n = 75) |
NonPF&S (n = 50) |
||
| Matrix 1 | PDGF-BB (ng/mL) | 3.1 (1.8) | 3.9 (2.5) |
| MIP-1β (ng/mL) | 175.6 (72.4) | 176.2 (76.7) | |
| Matrix 4 | Aspartic acid (μmol/L) | 23.9 (4.9) | 16.4 (3.6) |
| Matrix 3 | Hsp72 (ng/mL) | 1.4 (1.0) | 2.5 (1.7) |
| Matrix 2 | MPO (ng/mL) | 227.5 (182.3) | 667.3 (593.4) |
Matrices are ordered according to the sequence in which they were entered in the model. Bolded analytes are common to the two genders; gender-specific discriminant biomolecules are unbolded. Data are shown as median and interquartile range
CAF, C-terminal agrin fragment; FGF21, fibroblast growth factor 21; Hsp72, heat shock protein 72; MIP-1β, macrophage inflammatory protein 1β; MPO, myeloperoxidase; PDGF-BB, platelet-derived growth factor BB