Fig. 1.

Prenol supplementation increased lifespan of wild-type C. elegans and reduced amyloid aggregation in transgenic C. elegans strains. a Effect of Prenol on lifespan of wild-type C. elegans fed on live OP50. b Effect of Prenol on lifespan of wild-type C. elegans fed on heat-killed OP50. The 0.25 mM (P < 0.0001) concentration enhanced the lifespan of wild-type N2 worms most significantly in both the conditions c Effect of Prenol supplementation on the amyloid-β induced toxicity in C. elegans. Prenol treatment significantly delayed the amyloid-β induced paralysis in transgenic CL4176 transgenic strain. GraphPad Prism5 was used to plot survival curves. d Effect of Prenol supplementation on the α-Synuclein aggregation in NL5901 transgenic strain its graphical presentation as measured by ImageJ software. Prenol supplementation reduced the α-Synuclein aggregation in NL5901 transgenic strains. Statistically significant at **P < 0.001