Table 3.

Association between telomere length and the risk of frailty in TSHA and ENRICA participants

	TSHA cohort		ENRICA cohort
	OR [95% CI]	p value	OR [95% CI]	p value
Model 1	0.88 [0.71–1.10]	0.27	1.07 [0.88–1.31]	0.49
Model 2	0.96 [0.75–1.23]	0.75	1.07 [0.88–1.31]	0.49
Model 3	0.97 [0.75–1.27]	0.84	1.08 [0.88–1.31]	0.45
Model 4	0.96 [0.74–1.25]	0.78	1.09 [0.89–1.34]	0.42
Model 5	0.96 [0.73–1.24]	0.74	1.09 [0.89–1.34]	0.42

The association between telomere length and the risk for incident frailty was estimated by odds ratios (OR) and their 95% confidence intervals (CI, in brackets). Increase in TL by 1 kilobase was used for calculating OR. Model 1: non-adjusted model. Model 2: adjusted by age (years) and sex. Model 3: additionally adjusted by diabetes mellitus, cardiovascular disease, and cerebrovascular disease. Model 4: further adjusted by education level (higher than primary school). Model 5: further adjusted by disability in basic activities of daily living