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editorial
. 2021 Apr 27;8:686495. doi: 10.3389/fcvm.2021.686495

Figure 1.

Figure 1

COVID-19 on Comorbidities (created with Biorender.com). Cardiovascular injuries contribute to disease severity during SARS-CoV-2 infection. ACE2, Angiotensin-converting enzyme 2; TMPRSS2, Transmembrane serine protease 2; iPS-CMs, Human inducible pluripotent stem cell-derived cardiomyocytes; GFP-SARS-CoV-2, Green fluorescent protein bearing SARS-CoV-2 pseudovirus; TNFα, Tumor necrosis fator alfa; (IL)-6, (IL)-1β, Interleukin; MCP-1, Monocyte chemoattractant protein 1; VCAM-1, Vascular cell adhesion molecule-1; ICAM-1, Intercellular adhesion molecule-1; CCR2, Chemokine receptor type 2; ROS, Reactive oxygen species.