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. 2021 Apr 27;8:658900. doi: 10.3389/fcvm.2021.658900

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Copyright © 2021 Papazoglou, Peng and Sachinidis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) General epigenetic action mechanisms of histone acetylation and deacetylation. (B) Epigenetic action mechanisms of histone methylation [see section General Aspects of the Epigenetics (A,B): Core figure was obtained from OpenClipart-Vectors (https://pixabay.com/de/users/openclipart-vectors-30363/] and modified accordingly. (Me, methyl; HDAC, histone deacetylases; RNAPII, RNA polymerase II; PRC 2, polycomb repressive complex 2; HMTs, histone methyltransferases; HTAs).