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. 2021 Mar 15;124(10):1680–1689. doi: 10.1038/s41416-021-01307-y

Fig. 3. Tertiary lymphoid structures (TLS) score and clinical outcome.

Fig. 3

Glance overview on the positive prognostic impact of TLS in the overall cohort of NSCLC by different (semi)-quantification methods and stratification based on cohorts, other endpoints (OS overall survival, TTR time to recurrence), compartment, histology (LUSC lung squamous cell carcinoma, LUAD lung adenocarcinoma) and TNM subgroups. Log-rank P value of 5-years disease-specific survival (DSS) in parentheses. b DSS curves of the entire cohort and sub-cohorts (cohort #1 and #2) according to different scoring model of TLS. Left column, semi-quantitative (SQ); middle column, quantitative; right column, for germinal centre-positive subset (GC+ TLS) scoring models. The TLS scores were stratified using quartiles (models 1 and 2) and median cut-off (model 3) as indicated in the figure insets.