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. 2021 Mar 17;124(10):1699–1710. doi: 10.1038/s41416-021-01317-w

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Fig. 2 — a Semi-quantitative western blots depicting the SKP1 silencing efficiency of the individual (siSKP1–1, siSKP1–2, siSKP1–3 and siSKP1–4) and four pooled (siSKP1-Pool) siRNAs within FT194 (top) and FT246 (bottom) cell lines. Note the increases in Cyclin E1 levels within the SKP1 silenced cell populations. Fold changes in SKP1 or Cyclin E1 expression relative to siControl are indicated, using cyclophilin B or α-tubulin as loading controls. n = 3. b Semi-quantitative western blots depicting the CUL1 silencing efficiency of the individual (siCUL1–1, siCUL1–2, siCUL1–3 and siCUL1–4) and four pooled (siCUL1-Pool) siRNAs within FT194 (top) and FT246 (bottom) cell lines. Note the increases in Cyclin E1 levels within the CUL1 silenced cell populations. Fold changes in CUL1 or Cyclin E1 expression relative to siControl are indicated, using cyclophilin B as a loading control. n = 3.