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. 2021 May 10;11:9842. doi: 10.1038/s41598-021-89052-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differentially expressed genes in secondary follicle oocytes between mature and premature mice. (a) Representative pictures of the secondary follicles of (i) a mature mouse and (ii) premature mouse. Scale bars, 50 µm. (b) Heatmap of differentially expressed genes (DEGs, log2 fold change > 0.5, false discovery rate (FDR) < 0.01). Four samples from mature and premature mice were compared. (c) Expression levels of Figla in the secondary follicle oocytes of mature mice and premature mice by qRT-PCR (n = 6, in each group).