Table 4.
Top 35 upregulated DEG in NE challenged birds relative to non-challenged birds.
| Gene symbol | Gene name | Fold change | P-value | FDR |
|---|---|---|---|---|
| MYBPC1 | Myosin binding protein C, slow type | +3.616 | 0.0006 | 0.0128 |
| SLC10A2, ASBT | Solute carrier family 10 member 2 | +3.254 | 0.0005 | 0.0115 |
| ACOD1 | Aconitate decarboxylase 1 | +2.652 | 0.0002 | 0.0064 |
| ANKF1 | Ankyrin repeat and fibronectin type III domain containing 1 | +2.600 | 0.0000 | 0.0026 |
| IFN-γ | Interferon gamma | +2.590 | 0.0043 | 0.0352 |
| WASF1/wave 1 | WAS protein family member 1 | +2.199 | 0.0000 | 0.0027 |
| BEND4/ccdc4 | BEN domain containing 4 | +2.197 | 0.0003 | 0.0086 |
| TM4SF19 | Transmembrane 4 L six family member 19 | +2.110 | 0.0001 | 0.0056 |
| RNF208 | Ring finger protein 208 | +1.998 | 0.0000 | 0.0012 |
| KRT19 | Keratin 19 | +1.989 | 0.0053 | 0.0400 |
| LNX1 | Ligand of numb-protein X 1 | +1.932 | 0.0064 | 0.0449 |
| WNT5B | Wnt family member 5B | +1.914 | 0.0068 | 0.0463 |
| SLC7A5 | Solute carrier family 7 member 5 | +1.893 | 0.0000 | 0.0040 |
| SCN3B | Sodium voltage-gated channel beta subunit 3 | +1.888 | 0.0028 | 0.0276 |
| FRMD3 | FERM domain containing 3 | +1.874 | 0.0001 | 0.0054 |
| NEURL1B | Neuralized E3 ubiquitin protein ligase 1B | +1.804 | 0.0003 | 0.0084 |
| PLCD4 | Phospholipase C delta 4 | +1.717 | 0.0021 | 0.0235 |
| DUSP4 | Dual specificity phosphatase 4 | +1.659 | 0.0000 | 0.0039 |
| GZMA | Granzyme A | +1.655 | 0.0003 | 0.0082 |
| CEBPB | CCAAT enhancer binding protein beta | +1.634 | 0.0009 | 0.0152 |
| ASS1 | Argininosuccinate synthase 1 | +1.631 | 0.0001 | 0.0051 |
| HYAL3 | Hyaluronoglucosaminidase 3 | +1.551 | 0.0018 | 0.0221 |
| BCL2A1 | BCL2 related protein A1 | +1.545 | 0.0039 | 0.0334 |
| KCNJ5 | Potassium voltage-gated channel subfamily J member 5 | +1.516 | 0.0024 | 0.0254 |
| EOMES | Eomesodermin | +1.506 | 0.0020 | 0.0230 |
| THEMIS2 | Thymocyte selection associated family member 2 | +1.486 | 0.0000 | 0.0038 |
| SLC11A1 | Solute carrier family 11 member 1 | +1.486 | 0.0009 | 0.0154 |
| DCT | Dopachrome tautomerase | +1.479 | 0.0024 | 0.0253 |
| NRG1 | Neuregulin 1 | +1.474 | 0.0002 | 0.0076 |
| PROKR2 | Prokineticin receptor 2 | +1.473 | 0.0019 | 0.0223 |
| SCL6A7/LAT1 | Solute carrier family 6 member 7 | +1.458 | 0.0032 | 0.0300 |
| INSRR | Insulin receptor related receptor | +1.453 | 0.0000 | 0.0026 |
| ART1 | ADP-ribosyltransferase 1 | +1.429 | 0.0011 | 0.0168 |
| IL21R | Interleukin 21 receptor | +1.414 | 0.0018 | 0.0217 |
| NEXMIF | Neurite extension and migration factor | +1.389 | 0.0034 | 0.0305 |
DEG = differentially expressed genes; NE = necrotic enteritis; FDR = false discovery rate.