Table 1.
Dominant epitopes for highest scoring antigens from SLE PIWAS.
| Protein Name | Outlier Sum FDR | Dominant epitope(s) |
|---|---|---|
| Small nuclear ribonucleoprotein-associated proteins B and B’ | 9.9E-11 | GGPSQQVMTPQ, PGMRPPMGPPM |
| Small nuclear ribonucleoprotein-associated protein N | 2.3E-10 | GGPSQQVMTPQ, PPGMRPPPPGI |
| U1 small nuclear ribonucleoprotein C | 3.3E-10 | GMRPPMGGHMP |
| Doublecortin domain-containing protein 2C | 0.00027 | IKPVVHCDINV, YWKSPRVPSEV |
| Transmembrane anterior posterior transformation protein 1 homolog | 0.0013 | LLQPAQVCDIL |
| ADP-ribosylation factor-like protein 13B | 0.0026 | IASVIIENEGK |
| U1 small nuclear ribonucleoprotein A | 0.0028 | PPGMIPPPGLA, PGMIPPPGLAP |
| Ubiquitin carboxyl-terminal hydrolase 24 | 0.0039 | None |
| Uncharacterized protein | 0.0039 | None |
| DnaJ homolog subfamily C member 3 | 0.0039 | None |
| Ca(2+)-independent N-acyltransferase | 0.0058 | LIEGNCEHFVN |
| Iron-responsive element-binding protein 2 | 0.006 | None |
| CMT1A duplicated region transcript 4 protein | 0.0068 | YVTYTSQTVKR, RLIEKSKTREL, SSKSSGKAVFR |
| Presenilins-associated rhomboid-like protein, mitochondrial | 0.0073 | GRRFNFFIQQK |
| Tektin-1 | 0.011 | KKLEQRLEEVQ, NSVSLEDWLDF |
| Inositol hexakisphosphate kinase 3 | 0.012 | YDGPDPGYIFG |
| Transcription factor SOX-17 | 0.012 | QPSPPPEALPC, MGLPYQGHDSG |
| Kelch-like protein 20 | 0.013 | None |
| Estrogen-related receptor gamma | 0.015 | None |
| PAK4-inhibitor INKA2 | 0.016 | MDCYLRRLKQE, LQDQMNCMMGA, TKFPSHRSVCG |
| Gamma-butyrobetaine dioxygenase | 0.016 | TTGKLSFHTDY, DYCDFSVQSKH |
| 60S acidic ribosomal protein P1 | 0.016 | MGFGLFD |