Table 1.
Descriptive statistics for predictors and immunological measures (N = 159).
| Variable | Men (n = 80) | Women (n = 79) |
|---|---|---|
| M (SD) | M (SD) | |
| Childhood SES | 4.55 (1.46) | 4.55 (1.50) |
| Childhood unpredictability | 2.45 (1.16) | 2.29 (1.29) |
| Adverse childhood experiences | 4.05 (2.79) | 2.99 (2.90) |
| Phagocytosis of E. coli bioparticles (%) | 13.55 (6.40) | 11.64 (5.21) |
| NK cell cytotoxicity (%) | 38.55 (13.69) | 36.59 (16.55) |
| Unstimulated proliferation | 0.65 (0.14) | 0.71 (0.16) |
| Proliferation in response to LPS | 1.02 (0.19) | 1.01 (0.19) |
| Proliferation in response to PHA | 1.07 (0.17) | 1.10 (0.18) |
| Proliferation in response to Poly (I:C) | 0.79 (0.16) | 0.82 (0.14) |
| Unstimulated release of IL-1β | 73.23 (282.61) | 30.63 (60.36) |
| Unstimulated release of IL-6 | 472.32 (1410.60) | 135.35 (253.64) |
| Unstimulated release of TNF-α | 143.36 (215.26) | 126.31 (184.14) |
| LPS-stimulated release of IL-1β | 1468.77 (1384.79) | 1361.51 (1186.40) |
| LPS-stimulated release of IL-6 | 5307.71 (2415.50) | 4611.49 (2094.76) |
| LPS-stimulated release of TNF-α | 2125.59 (1213.38) | 1722.65 (1018.11) |
Peripheral blood mononuclear cell (PBMC) proliferation values shown here as absorbance reading at 490 nm collapsed across time-points (24 h, 48 h, 72 h) for each plating condition. Values for natural killer cell lysis of K-562 tumor cells (i.e., NK cell cytotoxicity) shown here collapsed across effector:target cell ratios (100:1, 50:1, 25:1, 12.5:1). Levels of cytokines released from PBMCs in vitro shown here as pg/mL. Proliferation values shown as optical density values (490 nm).
SES socioeconomic status, LPS lipopolysaccharide, PHA phytohemagglutinin, poly (I:C) polyinosinic:polycytidylic acid, NK natural killer, E. coli Escherichia coli, IL-1β interleukin-1 beta, IL-6 interleukin-6, TNF-α tumor necrosis factor-alpha.